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KMID : 0364020160490030207
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Korean Journal of Thoracic and Cardiovascular Surgery
2016 Volume.49 No. 3 p.207 ~ p.209
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Intracardiac Thrombosis Involving All Four Cardiac Chambers after Extracardiac Membranous Oxygenation Associated with MTHFR Mutations
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Kim Bong-Jun
Song Seung-hwan
Shin Yu-Rim
Park Han-Ki
Park Young-Hwan
Shin Hong-Ju
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Abstract
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A 4-month-old boy diagnosed with acute myocarditis was treated with extracorporeal membrane oxygenation (ECMO). Follow-up echocardiography eight hours after ECMO revealed intracardiac thrombosis involving all four heart chambers. Because of the high risk of systemic embolization due to a pedunculated thrombus of the aortic valve, we performed an emergency thrombectomy. After the operation, the patient had a minor neurologic sequela of left upper arm hypertonia, which had almost disappeared at the last outpatient clinic two months later. He was diagnosed with a major mutation in MTHFR (methylenetetrahydrofolate reductase), which is related to thrombosis.
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KEYWORD
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Myocarditis, Extracorporeal membrane oxygenation, Thrombosis, Methylenetetrahydrofolate reductase
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